INT351985

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Stk11) mitochondrion (Stk11) nucleus (Stk11)
cell cycle (Stk11) protein complex (Stk11) cytoplasm (Stk11)
Stk11 (Rattus norvegicus)
Dcc (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 11 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 2 98.76 Very High Very High Very High
Cardiovascular Disease 6 97.52 Very High Very High Very High
Stress 1 93.36 High High
Congenital Anomalies 1 89.96 High High
Hypoxia 1 89.68 High High
Embryonic Lethality 1 87.08 High High
Hyperplasia 2 81.84 Quite High
Syndrome 4 77.48 Quite High
Neointima 21 61.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpressed LKB1 increases expression of several p21 (CDK inhibitor), p53 responsive genes.8-11) This tumor suppressor protein may have an important role in atherosclerosis, especially in restenosis.
LKB1 Positive_regulation (increases) of Gene_expression (expression) of tumor suppressor protein associated with cardiovascular disease, cancer and increased venous pressure under development
1) Confidence 0.01 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC3008825 Disease Relevance 1.79 Pain Relevance 0

General Comments

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