INT352006

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Context Info
Confidence 0.31
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (Sox6) nucleus (Sox6) DNA binding (Sox6)
Anatomy Link Frequency
cartilage 1
Sox6 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 7 5.00 Very Low Very Low Very Low
backache 6 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 4 77.60 Quite High
Intervertebral Disk Degeneration 31 5.00 Very Low Very Low Very Low
Low Back Pain 6 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Calcification 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In mice lacking both Sox5 and Sox6, the notochordal sheath fails to form, probably due to associated downregulation of genes encoding cartilage matrix components such as collagen II and aggrecan (Smits and Lefebvre, 2003).
Negative_regulation (lacking) of Sox6 in cartilage
1) Confidence 0.31 Published 2011 Journal Disease Models & Mechanisms Section Body Doc Link PMC3008962 Disease Relevance 0.08 Pain Relevance 0

General Comments

This test has worked.

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