INT352031

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.87
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (NR3C1, JUND) cytosol (NR3C1) nucleoplasm (NR3C1)
signal transduction (NR3C1) aging (NR3C1) nucleolus (NR3C1)
Anatomy Link Frequency
epithelial cells 4
NR3C1 (Homo sapiens)
JUND (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 8 95.52 Very High Very High Very High
dexamethasone 8 73.36 Quite High
agonist 76 41.12 Quite Low
Inflammation 20 12.16 Low Low
corticosteroid 32 11.60 Low Low
antagonist 16 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Analgesic 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Catecholamine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Occupational Lung Diseases 20 100.00 Very High Very High Very High
Asthma 244 93.72 High High
Repression 12 91.84 High High
INFLAMMATION 20 12.16 Low Low
Disease 28 5.00 Very Low Very Low Very Low
Nicotine Addiction 12 5.00 Very Low Very Low Very Low
Dyspnea 8 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Cough 4 5.00 Very Low Very Low Very Low
Respiratory Sounds 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies have shown that the glucocorticoid receptor (GR) in GCR asthmatics exhibits a lower interaction with activator protein-1 (AP-1), and this effect is accompanied by raised levels of AP-1.[26] Mathieu et al. have shown that overexpression of the GR gene in A549 human lung epithelial cells, using a GR expression vector, resulted in repression of both nuclear factor kappa-B (NF-?
GCR Binding (interaction) of activator protein-1 in epithelial cells associated with repression and occupational lung diseases
1) Confidence 0.10 Published 2010 Journal Indian Journal of Human Genetics Section Body Doc Link PMC3009420 Disease Relevance 0.71 Pain Relevance 0.12
Studies have shown that the glucocorticoid receptor (GR) in GCR asthmatics exhibits a lower interaction with activator protein-1 (AP-1), and this effect is accompanied by raised levels of AP-1.[26] Mathieu et al. have shown that overexpression of the GR gene in A549 human lung epithelial cells, using a GR expression vector, resulted in repression of both nuclear factor kappa-B (NF-?
GR Binding (interaction) of activator protein-1 in epithelial cells associated with repression and occupational lung diseases
2) Confidence 0.10 Published 2010 Journal Indian Journal of Human Genetics Section Body Doc Link PMC3009420 Disease Relevance 0.72 Pain Relevance 0.12
Studies have shown that the glucocorticoid receptor (GR) in GCR asthmatics exhibits a lower interaction with activator protein-1 (AP-1), and this effect is accompanied by raised levels of AP-1.[26] Mathieu et al. have shown that overexpression of the GR gene in A549 human lung epithelial cells, using a GR expression vector, resulted in repression of both nuclear factor kappa-B (NF-?
GR Binding (interaction) of AP-1 in epithelial cells associated with repression and occupational lung diseases
3) Confidence 0.10 Published 2010 Journal Indian Journal of Human Genetics Section Body Doc Link PMC3009420 Disease Relevance 0.72 Pain Relevance 0.12
Studies have shown that the glucocorticoid receptor (GR) in GCR asthmatics exhibits a lower interaction with activator protein-1 (AP-1), and this effect is accompanied by raised levels of AP-1.[26] Mathieu et al. have shown that overexpression of the GR gene in A549 human lung epithelial cells, using a GR expression vector, resulted in repression of both nuclear factor kappa-B (NF-?
GCR Binding (interaction) of AP-1 in epithelial cells associated with repression and occupational lung diseases
4) Confidence 0.10 Published 2010 Journal Indian Journal of Human Genetics Section Body Doc Link PMC3009420 Disease Relevance 0.72 Pain Relevance 0.12

General Comments

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