INT352073

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.27
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CCL19) extracellular region (CCL19) plasma membrane (ADAM11)
Anatomy Link Frequency
lymph nodes 2
ADAM11 (Homo sapiens)
CCL19 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 6 100.00 Very High Very High Very High
Inflammatory response 2 97.92 Very High Very High Very High
cytokine 7 70.72 Quite High
agonist 6 38.32 Quite Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 96 99.32 Very High Very High Very High
Apoptosis 27 98.64 Very High Very High Very High
INFLAMMATION 3 97.74 Very High Very High Very High
Disease Progression 14 82.52 Quite High
Viral Infection 1 73.36 Quite High
Disease 25 65.84 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 41 65.04 Quite High
Immunodeficiency 4 50.00 Quite Low
Viral Meningitis 1 26.72 Quite Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, these data suggest that the inflammatory response associated with increased virus load during progressive SIV infection leads to an increase in the CCR7-CCL19 chemokine axis that serves to accelerate mDC recruitment to lymph nodes.
Positive_regulation (accelerate) of mDC Binding (recruitment) of CCL19 in lymph nodes associated with chemokine, inflammatory response and infection
1) Confidence 0.22 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC3009592 Disease Relevance 1.27 Pain Relevance 0.13

General Comments

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