INT352075

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.64
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (AGRP) extracellular region (AGRP) Golgi apparatus (AGRP)
plasma membrane (ADAM11)
Anatomy Link Frequency
blood 4
AGRP (Homo sapiens)
ADAM11 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 12 86.44 High High
cytokine 14 23.64 Low Low
agonist 12 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 192 97.36 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 82 95.84 Very High Very High Very High
Apoptosis 54 75.20 Quite High
Disease Progression 28 59.36 Quite High
Disease 50 54.28 Quite High
Immunodeficiency 8 50.00 Quite Low
Death 8 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Communicable Diseases 2 5.00 Very Low Very Low Very Low
Weight Loss 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In blood, ART reduced mDC activation and transiently restored mDC numbers in monkeys with progressive infection, consistent with reports in HIV-infected individuals [8], [17], [18].
ART Negative_regulation (reduced) of Positive_regulation (activation) of mDC in blood associated with acquired immune deficiency syndrome or hiv infection and infection
1) Confidence 0.06 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC3009592 Disease Relevance 0.87 Pain Relevance 0
The 12-week course ART was effective at reducing blood mDC activation, particularly with respect to CD80, and in animals in the stable group expression of all markers of activation returned to preinfection levels during ART (Figure 3A–C).
ART Negative_regulation (reducing) of Positive_regulation (activation) of mDC in blood
2) Confidence 0.05 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC3009592 Disease Relevance 0.77 Pain Relevance 0.04

General Comments

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