INT352086

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD40, ADAM11) signal transduction (CD40) extracellular region (CD40)
enzyme binding (CD40) protein complex assembly (CD40) signal transducer activity (CD40)
Anatomy Link Frequency
CD86 1
CD40 (Homo sapiens)
ADAM11 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 6 12.00 Low Low
cytokine 7 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 96 99.74 Very High Very High Very High
Disease 25 98.66 Very High Very High Very High
Disease Progression 14 91.16 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 41 64.24 Quite High
Immunodeficiency 4 50.00 Quite Low
Apoptosis 27 43.68 Quite Low
Death 4 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Communicable Diseases 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the phenotype of mDC within lymph nodes was significantly different as a function of disease, as animals with stable but not progressive infection had a lower percentage of mDC expressing CCR7, CD40 and CD86 and reduced mDC expression of MHC class II at 12 weeks relative to preinfection time points, reflecting reduced mDC activation (Figure 4C, D).
CD40 Binding (percentage) of mDC in CD86 associated with disease and infection
1) Confidence 0.08 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC3009592 Disease Relevance 0.77 Pain Relevance 0

General Comments

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