INT352163

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SNRPA) intracellular (IL10) cell-cell signaling (IL10)
response to stress (IL10) extracellular space (IL10) extracellular region (IL10)
Anatomy Link Frequency
T cells 2
SNRPA (Homo sapiens)
IL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 2 100.00 Very High Very High Very High
Arthritis 3 95.56 Very High Very High Very High
Inflammation 4 93.16 High High
Multiple sclerosis 1 92.48 High High
rheumatoid arthritis 5 81.84 Quite High
anakinra 1 47.12 Quite Low
Infliximab 1 39.72 Quite Low
cytokine 1 32.48 Quite Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nephritis 6 96.12 Very High Very High Very High
Arthritis 3 95.56 Very High Very High Very High
Inflammatory Bowel Disease 1 93.72 High High
Demyelinating Disease 1 92.48 High High
Rheumatoid Arthritis 5 81.84 Quite High
Systemic Lupus Erythematosus 56 77.44 Quite High
Graft Vs Host Disease 1 70.88 Quite High
Paroxysmal Nocturnal Hemoglobinuria 1 43.12 Quite Low
Synovitis 1 41.88 Quite Low
Necrosis 1 38.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lupuzor (Cephalon, Frazer, PA, USA) is a splicosomal peptide with U1 snRNP that promotes tolerance by preventing the proliferation of CD4+ T cells, as well as promoting secretion of IL-10 and decreasing anti-DNA in a European study.
U1 snRNP Positive_regulation (promoting) of Localization (secretion) of IL-10 in T cells associated with tolerance
1) Confidence 0.06 Published 2010 Journal BMC Med Section Body Doc Link PMC3009611 Disease Relevance 0.87 Pain Relevance 0.23

General Comments

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