INT352180

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.06
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GLA) extracellular region (GLA) Golgi apparatus (GLA)
lysosome (GLA) cytoplasm (GLA)
GLA (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 60 65.48 Quite High
abdominal pain 4 62.56 Quite High
imagery 46 5.00 Very Low Very Low Very Low
depression 16 5.00 Very Low Very Low Very Low
fibrosis 14 5.00 Very Low Very Low Very Low
cva 12 5.00 Very Low Very Low Very Low
Neuropathic pain 8 5.00 Very Low Very Low Very Low
aspirin 8 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
Analgesic 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Proteinuria 42 94.52 High High
Renal Disease 52 91.44 High High
Disorders Of Creatine Metabolism 2 81.60 Quite High
Fabry Disease 384 79.84 Quite High
Diarrhoea 8 71.60 Quite High
Pain 70 65.48 Quite High
Abdominal Pain 4 62.56 Quite High
Disease 94 43.40 Quite Low
Chronic Renal Failure 32 25.76 Quite Low
Hypohidrosis 6 14.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In patients whose renal function continues to decline while receiving agalsidase alfa at 0.2 mg/kg (eGFR decline of ?
Negative_regulation (receiving) of Gene_expression (alfa) of agalsidase
1) Confidence 0.42 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC3009617 Disease Relevance 0.93 Pain Relevance 0.13
The supply of agalsidase beta has been reduced, since June 2009, due to production problems.
Negative_regulation (reduced) of Gene_expression (production) of agalsidase beta
2) Confidence 0.36 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC3009617 Disease Relevance 0.13 Pain Relevance 0

General Comments

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