INT352354

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EGFR, CNR1) signal transducer activity (EGFR, CNR1) response to stress (EGFR, CNR1)
aging (CNR1) extracellular space (EGFR) nucleus (EGFR)
EGFR (Homo sapiens)
CNR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Endocannabinoid 8 98.06 Very High Very High Very High
agonist 2 88.20 High High
Cannabinoid 18 68.24 Quite High
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 42 100.00 Very High Very High Very High
Disease 31 98.52 Very High Very High Very High
Prostate Cancer 21 88.24 High High
Malignant Neoplastic Disease 4 86.32 High High
Bordatella Infection 1 82.68 Quite High
Metastasis 4 66.08 Quite High
Adenocarcinoma 1 57.80 Quite High
Colon Cancer 2 52.72 Quite High
Death 6 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Given the local protective role of endocannabinoids in the prostate (see above), this study raises the possibility that differences in the relative expression of CB1 receptors and pEGFR in the tumour tissue may affect the pathogenesis and outcome of the disease.
pEGFR Spec (may) Regulation (affect) of Gene_expression (expression) of CB1 associated with endocannabinoid, cancer and disease
1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009725 Disease Relevance 1.16 Pain Relevance 0.17

General Comments

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