INT352355

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

response to stress (CNR1, EGFR) signal transducer activity (CNR1, EGFR) plasma membrane (CNR1, EGFR)
endosome (EGFR) cell morphogenesis (EGFR) aging (CNR1)
CNR1 (Homo sapiens)
EGFR (Homo sapiens)
Pain Link Frequency Relevance Heat
Endocannabinoid 8 77.12 Quite High
Cannabinoid 18 74.80 Quite High
agonist 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 31 99.76 Very High Very High Very High
Cancer 42 96.60 Very High Very High Very High
Anaplastic Astrocytoma 1 78.96 Quite High
Apoptosis 4 57.12 Quite High
Glioma 1 56.16 Quite High
Colon Cancer 2 37.64 Quite Low
Hepatocellular Cancer 1 33.64 Quite Low
Solid Tumor 1 32.16 Quite Low
Prostate Cancer 21 25.68 Quite Low
Adhesions 1 9.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The observation in the present study that a high, rather than a low, CB1IR compounds the effect of pEGFR upon disease severity and outcome is at first sight rather difficult to explain, since a high CB1 receptor expression would be expected to be protective, rather than damaging.
CB1IR Binding (compounds) of pEGFR associated with disease
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009725 Disease Relevance 0.76 Pain Relevance 0.20

General Comments

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