INT352384

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
fibroblasts 1
MIR539 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 1 70.56 Quite High
ischemia 8 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 5 7.76 Low Low
Cv Unclassified Under Development 8 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Coronary Artery Disease 4 5.00 Very Low Very Low Very Low
Myocardial Infarction 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Aging 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Heart Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The targets of miR-539 obtained by computational analyses include matrix metallopeptidase 20, fibroblast growth factor 14, clathrin, light polypeptide, osteoprotegerin and transcription factors like forkhead box B1, which may have roles in cardiac remodeling. miR-21 were shown to regulate the ERK-MAP kinase signalling pathway in cardiac fibroblasts, which has role on global cardiac structure and function [24].
Regulation (targets) of miR-539 in fibroblasts
1) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009730 Disease Relevance 0 Pain Relevance 0.04

General Comments

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