INT352387

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.25
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CFP, HPSE) extracellular space (CFP) hydrolase activity, acting on glycosyl bonds (HPSE)
cell adhesion (HPSE) nucleus (HPSE) carbohydrate metabolic process (HPSE)
Anatomy Link Frequency
amygdala 1
hippocampus 1
CFP (Homo sapiens)
HPSE (Homo sapiens)
Pain Link Frequency Relevance Heat
amygdala 38 100.00 Very High Very High Very High
Hippocampus 32 100.00 Very High Very High Very High
depression 154 91.92 High High
withdrawal 32 35.60 Quite Low
Neurotransmitter 16 5.00 Very Low Very Low Very Low
Dopamine 12 5.00 Very Low Very Low Very Low
Serotonin 12 5.00 Very Low Very Low Very Low
monoamine 10 5.00 Very Low Very Low Very Low
antidepressant 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 224 91.92 High High
Stress 24 65.20 Quite High
Neurodegenerative Disease 8 60.96 Quite High
Mental Disorders 4 40.00 Quite Low
Injury 2 15.68 Low Low
Death 2 13.56 Low Low
Anxiety Disorder 16 5.00 Very Low Very Low Very Low
Cognitive Disorder 14 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Built upon the notions of sickness behaviour as providing a benefit to the infected organism, the concomitant neurobiological alterations to structure and function of various brain regions (principally the PFC, hippocampus and amygdala) that accompany elevated HPA-axis activation following the onset of uncontrollable and highly aversive environmental stressors, may be seen to link observable behaviour with brain function to provide a more comprehensive model of depression.
PFC Binding (accompany) of HPA in amygdala associated with depression, hippocampus and amygdala
1) Confidence 0.01 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC3009949 Disease Relevance 0.62 Pain Relevance 0.23
Built upon the notions of sickness behaviour as providing a benefit to the infected organism, the concomitant neurobiological alterations to structure and function of various brain regions (principally the PFC, hippocampus and amygdala) that accompany elevated HPA-axis activation following the onset of uncontrollable and highly aversive environmental stressors, may be seen to link observable behaviour with brain function to provide a more comprehensive model of depression.
PFC Binding (accompany) of HPA in hippocampus associated with depression, hippocampus and amygdala
2) Confidence 0.00 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC3009949 Disease Relevance 0.62 Pain Relevance 0.23

General Comments

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