INT35246

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Context Info
Confidence 0.23
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.82
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PTGFR) plasma membrane (PTGFR) cytoplasm (PTGFR)
signal transducer activity (PTGFR)
Anatomy Link Frequency
hair 1
uterine 1
PTGFR (Homo sapiens)
Pain Link Frequency Relevance Heat
Dismenorea 7 99.82 Very High Very High Very High
antagonist 2 67.84 Quite High
metalloproteinase 2 67.68 Quite High
withdrawal 4 64.80 Quite High
Endocannabinoid 4 35.20 Quite Low
Pain 2 29.76 Quite Low
Inflammation 8 5.00 Very Low Very Low Very Low
headache 8 5.00 Very Low Very Low Very Low
Angina 6 5.00 Very Low Very Low Very Low
Migraine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dysmenorrhea 5 99.82 Very High Very High Very High
Alopecia 30 94.76 High High
Hirsutism 34 86.04 High High
Hemorrhage 4 67.04 Quite High
Ocular Hypertension 14 65.64 Quite High
Hypotension 8 64.48 Quite High
Glaucoma 36 62.16 Quite High
Pain 2 29.76 Quite Low
Hypotrichosis 24 5.00 Very Low Very Low Very Low
Alopecia Areata 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another possible explanation is that bimatoprost sensitivity may be conferred by interacting with FP-altFP heterodimer receptor instead, and the additional secondary calcium signaling pathway elicited by bimatoprost may translate into a stronger response of hair growth.
FP-altFP heterodimer receptor Binding (interacting) of in hair associated with alopecia
1) Confidence 0.23 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2861943 Disease Relevance 0.35 Pain Relevance 0
It appears that the FP-altFP4 heterodimer maintains responsiveness to PGF2?
FP-altFP4 Binding (heterodimer) of
2) Confidence 0.23 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2861943 Disease Relevance 0.13 Pain Relevance 0.07
Oral contraceptives reduce menstrual pain but the interaction with vasopressin and prostaglandin F2 alpha, two uterine stimulants related to the condition, is unknown.
prostaglandin F2 alpha Binding (interaction) of in uterine associated with dismenorea
3) Confidence 0.02 Published 1987 Journal J. Endocrinol. Section Abstract Doc Link 3125302 Disease Relevance 0.33 Pain Relevance 0.30

General Comments

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