INT352464

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.55
Pain Relevance 1.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Slc1a3)
Gse1 (Rattus norvegicus)
Slc1a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 42 100.00 Very High Very High Very High
Glutamate 16 100.00 Very High Very High Very High
Opioid 4 97.52 Very High Very High Very High
Neuropeptide 6 96.88 Very High Very High Very High
substance P 4 95.92 Very High Very High Very High
Inflammation 28 94.48 High High
trigeminal ganglion 12 94.12 High High
Snapping jaw 32 89.68 High High
nMDA receptor 2 88.56 High High
Inflammatory response 6 81.60 Quite High
Disease Link Frequency Relevance Heat
Nociception 28 98.24 Very High Very High Very High
INFLAMMATION 46 94.48 High High
Ganglion Cysts 12 94.12 High High
Temporomandibular Joint Syndrome 26 89.68 High High
Cognitive Disorder 4 9.92 Low Low
Pain 20 5.00 Very Low Very Low Very Low
Temporomandibular Joint Disorders 18 5.00 Very Low Very Low Very Low
Chronic Disease 6 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Significantly, we also found that GSE caused increased expression of the glutamate transporter GLAST that functions to regulate the amount of extracellular glutamate.
GSE Positive_regulation (caused) of Gene_expression (expression) of GLAST associated with glutamate
1) Confidence 0.05 Published 2010 Journal Mol Pain Section Body Doc Link PMC3009976 Disease Relevance 0.55 Pain Relevance 0.88
Another interesting finding from our study was that dietary GSE decreases basal expression of the MAP kinase-responsive gene CGRP, while increasing expression of GLAST in the TNC.
GSE Positive_regulation (increasing) of Gene_expression (expression) of GLAST associated with calcitonin gene-related peptide
2) Confidence 0.03 Published 2010 Journal Mol Pain Section Body Doc Link PMC3009976 Disease Relevance 1.00 Pain Relevance 0.95

General Comments

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