INT352467

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Dusp1, Mapk8) cytosol (Mapk8) nucleoplasm (Dusp1)
signal transduction (Mapk8) mitochondrion (Mapk8) cell cycle (Dusp1)
Dusp1 (Rattus norvegicus)
Mapk8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory response 3 90.76 High High
fifth nerve 1 85.28 High High
central sensitization 14 61.68 Quite High
trigeminal ganglion 6 50.00 Quite Low
Inflammation 14 7.36 Low Low
dexamethasone 1 5.44 Low Low
Calcitonin gene-related peptide 21 5.00 Very Low Very Low Very Low
Snapping jaw 16 5.00 Very Low Very Low Very Low
Spinal cord 8 5.00 Very Low Very Low Very Low
Glutamate 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 23 90.36 High High
Cognitive Disorder 2 82.28 Quite High
Nociception 14 53.92 Quite High
Ganglion Cysts 6 50.00 Quite Low
Temporomandibular Joint Syndrome 13 5.00 Very Low Very Low Very Low
Pain 10 5.00 Very Low Very Low Very Low
Temporomandibular Joint Disorders 9 5.00 Very Low Very Low Very Low
Chronic Disease 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MKP-1 is reported to dephosphorylate, and therefore, inactivate several MAP kinases including p38, JNK, and ERK, in a concentration dependent manner [33].
MKP-1 Negative_regulation (inactivate) of JNK
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC3009976 Disease Relevance 0.23 Pain Relevance 0.12

General Comments

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