INT3525

Context Info Confidence 0.58 First Reported 1976 Last Reported 2004 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.62 Pain Relevance 0.23

small molecule metabolic process (NEU1) hydrolase activity, acting on glycosyl bonds (NEU1) cytoplasmic membrane-bounded vesicle (NEU1) plasma membrane (NEU1) lysosome (NEU1)

NEU1 (Homo sapiens)

Pain Link Frequency Relevance Heat Neuritis 1 63.28 rheumatoid arthritis 39 56.44 Osteoarthritis 37 55.28 Pain 2 42.00 cytokine 1 39.76 Inflammation 6 5.00 Analgesic 1 5.00 cINOD 1 5.00 Rheumatism 1 5.00 Arthritis 1 5.00

Disease Link Frequency Relevance Heat Mycobacterium Infection 2 84.92 Infection 1 75.00 Arthropathy 3 61.60 Rheumatoid Arthritis 39 56.44 Osteoarthritis 37 55.28 Arthralgia 1 42.00 Shock 1 12.60 INFLAMMATION 7 5.00 Arthritis 3 5.00 Pain 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Some of the phagosomes contained granular, membranous, and vesicular debris considered to be bacillary degradation products, suggesting that lysosomal activity was present within the phagosomes.

Protein_catabolism (degradation) of lysosomal

1) Confidence 0.58 Published 1976 Journal Arch. Pathol. Lab. Med. Section Abstract Doc Link 786213 Disease Relevance 0.23 Pain Relevance 0.06

Hyaluronidase, which specifically degrades hyaluronan, is a lysosomal enzyme.

Protein_catabolism (degrades) of lysosomal enzyme

2) Confidence 0.01 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC1064865 Disease Relevance 0.39 Pain Relevance 0.16

General Comments

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