INT352501

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Context Info
Confidence 0.04
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.36
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (INS) carbohydrate metabolic process (INS) cell-cell signaling (INS)
cytosol (PRKAB1) signal transduction (PRKAB1) extracellular space (INS)
Anatomy Link Frequency
muscle 1
PRKAB1 (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 86.16 High High
cytokine 2 85.12 High High
tolerance 16 19.88 Low Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 17 95.28 Very High Very High Very High
Diabetes Mellitus 43 94.92 High High
Cancer 4 89.52 High High
Necrosis 4 89.04 High High
INFLAMMATION 5 86.16 High High
Frailty 11 86.04 High High
Aging 19 74.12 Quite High
Insulin Resistance 1 45.76 Quite Low
Parkinson's Disease 2 40.52 Quite Low
Impaired Glucose Tolerance 29 19.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-AMP-activated protein kinase (AMPK), which activates insulin-independent glucose uptake by the muscle, downregulates gluconeogenic enzymes and increases muscle fatty acid oxidation [83].
AMP-activated protein kinase Positive_regulation (activates) of insulin in muscle
1) Confidence 0.04 Published 2011 Journal Journal of Aging Research Section Body Doc Link PMC3010636 Disease Relevance 1.36 Pain Relevance 0.12

General Comments

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