INT352525

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Context Info
Confidence 0.00
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (SLC25A16) mitochondrion (SLC25A16) small molecule metabolic process (SLC25A16)
Golgi apparatus (SMO) plasma membrane (SMO) cilium (SMO)
Anatomy Link Frequency
basal cell 1
SLC25A16 (Homo sapiens)
SMO (Homo sapiens)
Pain Link Frequency Relevance Heat
cryotherapy 8 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 101 98.00 Very High Very High Very High
Necrosis 1 73.16 Quite High
Apoptosis 2 72.68 Quite High
Death 1 72.12 Quite High
Toxicity 1 69.20 Quite High
Syndrome 11 54.16 Quite High
Carcinoma 2 52.40 Quite High
Focal Dermal Hypoplasia 1 48.64 Quite Low
Basal Cell Nevus Syndrome 1 47.20 Quite Low
Eczema 1 44.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Von Hoff et al. [76] assessed the safety and pharmacokinetics of GDC-0449 (vismodegib), a small-molecule inhibitor of SMO, and responses of metastatic or locally advanced basal cell carcinoma to the drug.
GDC-0449 Negative_regulation (inhibitor) of SMO in basal cell associated with skin cancer
1) Confidence 0.00 Published 2011 Journal Journal of Skin Cancer Section Body Doc Link PMC3010650 Disease Relevance 1.10 Pain Relevance 0

General Comments

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