INT352608

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Context Info
Confidence 0.27
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Pdgfra) nucleus (Pdgfra) extracellular matrix organization (Pdgfra)
kinase activity (Pdgfra) cytoplasm (Pdgfra)
Anatomy Link Frequency
oligodendrocyte 1
Pdgfra (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 5 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 45 93.20 High High
Targeted Disruption 9 76.16 Quite High
Cancer 72 72.24 Quite High
Brain Tumor 60 62.32 Quite High
Glioblastoma 18 38.48 Quite Low
Oligodendroglioma 5 21.04 Low Low
Apoptosis 26 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low
Aging 7 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, by the help of high-throughput genome and transcriptome analyses, human secondary GBs were shown to be similar to the proneural type of primary GBs and associated with PDGFRA amplification, TP53 and PTEN deletion/mutation, IDH1 mutation and also disturbances in the PI3K signaling pathway, and finally by the expression of oligodendrocyte markers [133].
PDGFRA Binding (associated) of in oligodendrocyte
1) Confidence 0.27 Published 2011 Journal Journal of Oncology Section Body Doc Link PMC3010739 Disease Relevance 0.70 Pain Relevance 0

General Comments

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