INT352615

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Context Info
Confidence 0.30
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme binding (Mdm4, Trp53) protein complex assembly (Mdm4, Trp53) nucleus (Mdm4, Trp53)
nucleoplasm (Trp53) mitochondrion (Trp53) endoplasmic reticulum (Trp53)
Mdm4 (Mus musculus)
Trp53 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 5 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Viral Infection 1 97.96 Very High Very High Very High
Cancer 72 94.68 High High
Glioma 45 81.84 Quite High
Syndrome 2 78.56 Quite High
Apoptosis 26 74.36 Quite High
Aging 7 73.92 Quite High
Stress 8 69.08 Quite High
Ependymoma 2 65.48 Quite High
Anaplastic Astrocytoma 4 64.80 Quite High
Medulloblastoma 1 63.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The MDM4 and MDM2 proteins suppress p53's transcriptional activity and target p53 for proteasomal degradation, respectively [22].
MDM4 Binding (target) of p53
1) Confidence 0.30 Published 2011 Journal Journal of Oncology Section Body Doc Link PMC3010739 Disease Relevance 1.36 Pain Relevance 0

General Comments

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