INT352622

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Context Info
Confidence 0.06
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Olig2, Tpt1) nucleoplasm (Tpt1) extracellular space (Tpt1)
plasma membrane (Olig2) nucleus (Olig2) DNA binding (Olig2)
Olig2 (Mus musculus)
Tpt1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 1 96.76 Very High Very High Very High
Central nervous system 5 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Tumor 60 96.96 Very High Very High Very High
Glioma 45 95.28 Very High Very High Very High
Stress 8 84.88 Quite High
Cancer 72 58.88 Quite High
Malignant Neoplastic Disease 5 46.80 Quite Low
Glioblastoma 18 44.92 Quite Low
Apoptosis 26 36.88 Quite Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Aging 7 5.00 Very Low Very Low Very Low
Oligodendroglioma 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Olig2 directly suppresses p21, a downstream key target of p53, and Olig2 is therefore presumably an important antagonist of the p53 pathway during glioma development [113].
Olig2 Negative_regulation (suppresses) of p21 associated with antagonist and glioma
1) Confidence 0.06 Published 2011 Journal Journal of Oncology Section Body Doc Link PMC3010739 Disease Relevance 0.54 Pain Relevance 0.05

General Comments

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