INT352662

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (FMR1) transport (FMR1) mRNA binding (FMR1)
nucleolus (FMR1) RNA binding (FMR1) nucleus (FMR1)
FMR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
long-term potentiation 14 54.08 Quite High
Hippocampus 4 45.12 Quite Low
amygdala 58 5.00 Very Low Very Low Very Low
nMDA receptor 25 5.00 Very Low Very Low Very Low
Glutamate 21 5.00 Very Low Very Low Very Low
withdrawal 9 5.00 Very Low Very Low Very Low
Pyramidal cell 8 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
medulla 6 5.00 Very Low Very Low Very Low
anticonvulsant 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fragile X Syndrome 3 99.44 Very High Very High Very High
Autism 314 93.48 High High
Intellectual Impairment 24 61.76 Quite High
Syndrome 21 57.12 Quite High
Retts Disease 6 54.36 Quite High
Learning Disorders 1 17.52 Low Low
Anxiety Disorder 52 5.00 Very Low Very Low Very Low
Cognitive Disorder 43 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 11 5.00 Very Low Very Low Very Low
Phobia 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To further study the neurobiological causes of Fragile X Syndrome a mutant mouse was created lacking the expression of the FMR1 gene (Consortium, 1994).
Negative_regulation (lacking) of Gene_expression (expression) of FMR1 gene associated with fragile x syndrome
1) Confidence 0.31 Published 2010 Journal Frontiers in Human Neuroscience Section Body Doc Link PMC3010743 Disease Relevance 1.05 Pain Relevance 0.03

General Comments

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