INT352750

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pkd2, Vegfa) plasma membrane (Pkd2, Vegfa) cell differentiation (Vegfa)
transport (Pkd2) endoplasmic reticulum (Pkd2) cilium (Pkd2)
Pkd2 (Mus musculus)
Vegfa (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 1 98.76 Very High Very High Very High
Cholecystokinin 1 94.16 High High
imagery 11 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 1 100.00 Very High Very High Very High
Reprotox - General 1 1 99.36 Very High Very High Very High
Pancreatic Cancer 1 99.28 Very High Very High Very High
Neuroendocrine Cancer 1 96.72 Very High Very High Very High
Infection 33 74.80 Quite High
Fungal Infection 19 33.84 Quite Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Candida Infection 5 5.00 Very Low Very Low Very Low
Cryptococcus Infection 5 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, PKD1 has been involved in secretion of matrix metalloproteinase-2 and -9 from prostate cancer cells [61] or of insulin [62]; PKD2 was shown to regulate hypoxia-induced VEGF-A secretion from pancreatic tumor cells [63] or secretion of chromogranin A from neuroendocrine tumor cells [64]; and PKD3 promoted secretion of cholecystokinin-mediated pancreatic amylase [65].
PKD2 Positive_regulation (induced) of VEGF associated with neuroendocrine cancer, hypoxia, pancreatic cancer, metalloproteinase, cholecystokinin and reprotox - general 1
1) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3011003 Disease Relevance 0.47 Pain Relevance 0.10

General Comments

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