INT352752

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Prkd1) nucleus (Prkd1) intracellular (Prkd1)
kinase activity (Prkd1) cytoplasm (Prkd1)
Anatomy Link Frequency
plasma 2
Sms (Mus musculus)
Prkd1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 11 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Cholecystokinin 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fungal Infection 19 97.00 Very High Very High Very High
Infection 33 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Candida Infection 5 5.00 Very Low Very Low Very Low
Cryptococcus Infection 5 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low
Granuloma 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Communicable Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In previous studies, we showed that DAG produced in the Golgi by SMS favors PKD1 translocation to this organelle [30] where it initiates trans Golgi network (TGN)-mediated secretion [57], [58] and we also observed that SMS1 and SMS2 modulate protein trafficking from the TGN to the plasma membrane and secretion (Marimuthu, Qureshi and Luberto, submitted).
SMS Positive_regulation (favors) of Localization (translocation) of PKD1 in plasma
1) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3011003 Disease Relevance 0.24 Pain Relevance 0

General Comments

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