INT352793

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.76
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (APOC1, FGF21) signal transduction (FGF21) transport (APOC1)
endoplasmic reticulum (APOC1) cell-cell signaling (FGF21) lipid metabolic process (APOC1)
APOC1 (Homo sapiens)
FGF21 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 4 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 48 100.00 Very High Very High Very High
Obesity 38 98.36 Very High Very High Very High
Hypertension 28 98.04 Very High Very High Very High
Diabetes Mellitus 30 97.36 Very High Very High Very High
Coronary Artery Disease 96 95.96 Very High Very High Very High
Heart Disease 2 71.20 Quite High
Cardiovascular Disease 8 64.56 Quite High
Insulin Resistance 6 24.24 Low Low
Myocardial Infarction 6 5.00 Very Low Very Low Very Low
Metabolic Syndrome 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Logistic regression analysis demonstrated that FGF-21 showed an independent association with triglyceride and apolipoprotein A1.


apolipoprotein A1 Binding (association) of FGF-21 associated with disorder of lipid metabolism
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC3012070 Disease Relevance 1.59 Pain Relevance 0
First, we demonstrate that in addition to fasting glucose, both apolipoprotein A1 and triglyceride are significantly associated with circulating FGF-21 in our research subjects independent of BMI, HDL cholesterol and insulin in multivariate analysis.
apolipoprotein A1 Binding (associated) of FGF-21 associated with obesity and disorder of lipid metabolism
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012070 Disease Relevance 1.17 Pain Relevance 0

General Comments

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