INT352890

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ROS1) isomerase activity (PTGDS) transport (PTGDS)
Golgi apparatus (PTGDS) cytoplasm (PTGDS) cell proliferation (ROS1)
Anatomy Link Frequency
chondrocytes 1
PTGDS (Homo sapiens)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 64 88.44 High High
Inflammation 9 71.68 Quite High
COX-2 inhibitor 3 48.72 Quite Low
cytokine 3 39.52 Quite Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 19 96.16 Very High Very High Very High
Osteoarthritis 71 88.44 High High
INFLAMMATION 11 71.68 Quite High
Apoptosis 11 70.32 Quite High
Disease 4 43.32 Quite Low
Arthropathy 1 38.32 Quite Low
Death 7 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Knockdown of L-prostaglandin synthase (L-PGDS) via RNA interference abrogated the formation of ROS in sheared T/C-28a2 chondrocytes (Fig. 4).
L-PGDS Binding (formation) of ROS in chondrocytes
1) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012157 Disease Relevance 0.67 Pain Relevance 0.25

General Comments

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