INT352912

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (RETNLB) extracellular region (RETNLB) molecular_function (RETNLB)
cellular_component (RETNLB)
Anatomy Link Frequency
chondrocytes 1
RETNLB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 100.00 Very High Very High Very High
Osteoarthritis 64 91.04 High High
Inflammation 9 61.12 Quite High
addiction 1 19.92 Low Low
COX-2 inhibitor 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 11 100.00 Very High Very High Very High
Apoptosis 11 99.44 Very High Very High Very High
Sprains And Strains 4 96.00 Very High Very High Very High
Stress 19 95.36 Very High Very High Very High
Osteoarthritis 71 91.04 High High
Death 7 78.76 Quite High
Toxicity 1 27.64 Quite Low
Disease 4 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exposure of human chondrocytes to high fluid shear elicits the release of pro-inflammatory mediators such as interleukin-6 [5], and mediates matrix degradation [4], [6] and apoptosis [7], [8], [9].
Protein_catabolism (degradation) of pro-inflammatory in chondrocytes associated with inflammatory mediators and apoptosis
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012157 Disease Relevance 1.14 Pain Relevance 0.32

General Comments

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