INT352919

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.21
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (RHOB) endosome (RHOB) intracellular (RHOB)
GTPase activity (RHOB) cytosol (RHOB) cell adhesion (RHOB)
RHOB (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 128 100.00 Very High Very High Very High
rheumatoid arthritis 6 96.72 Very High Very High Very High
Inflammatory response 2 80.32 Quite High
chemokine 2 34.00 Quite Low
Inflammation 18 5.00 Very Low Very Low Very Low
COX-2 inhibitor 6 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 142 100.00 Very High Very High Very High
Rheumatoid Arthritis 6 96.72 Very High Very High Very High
INFLAMMATION 22 79.96 Quite High
Death 14 76.36 Quite High
Adhesions 4 75.52 Quite High
Apoptosis 22 43.52 Quite Low
Stress 38 5.00 Very Low Very Low Very Low
Sprains And Strains 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, our data are consistent with prior observations suggesting that RHOB, a member of the Rho GTP-binding protein, is overexpressed in OA [17], [18] and the positive association in the expression levels of RHOB and PARP-1 [19].
Positive_regulation (overexpressed) of Gene_expression (levels) of RHOB associated with osteoarthritis
1) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012157 Disease Relevance 1.11 Pain Relevance 0.48
Moreover, our data are consistent with prior observations suggesting that RHOB, a member of the Rho GTP-binding protein, is overexpressed in OA [17], [18] and the positive association in the expression levels of RHOB and PARP-1 [19].
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of RHOB associated with osteoarthritis
2) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012157 Disease Relevance 1.10 Pain Relevance 0.47

General Comments

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