INT352944

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Akt1) transport (Akt1) aging (Akt1)
enzyme binding (Akt1) carbohydrate metabolic process (Akt1) cytoplasm (Akt1)
Sh2d6 (Rattus norvegicus)
Akt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 47 75.96 Quite High
adenocard 7 5.00 Very Low Very Low Very Low
bradykinin 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 45 75.96 Quite High
Myocardial Infarction 8 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Reperfusion Injury 3 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Infarction 1 5.00 Very Low Very Low Very Low
Coronary Heart Disease 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SH-6 is a phosphatidylinositol (PI) analog that inhibits Akt without affecting the activity of its upstream kinase PDK-1 [16], and has also been shown to prevent phosphorylation of Akt at Ser473 [4, 32].
SH-6 Negative_regulation (prevent) of Phosphorylation (phosphorylation) of Akt
1) Confidence 0.06 Published 2010 Journal Basic Res Cardiol Section Body Doc Link PMC3012213 Disease Relevance 0.08 Pain Relevance 0.04

General Comments

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