INT353037

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL4, IL2) extracellular region (IL4, IL2) cell adhesion (IL2)
cell-cell signaling (IL2)
Anatomy Link Frequency
capillary 1
IL4 (Homo sapiens)
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 7 97.68 Very High Very High Very High
chemokine 1 95.24 Very High Very High Very High
Inflammation 5 65.92 Quite High
ischemia 1 62.32 Quite High
antagonist 6 44.24 Quite Low
Inflammatory response 1 18.32 Low Low
corticosteroid 3 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 1 100.00 Very High Very High Very High
Cancer 1 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 1 92.32 High High
Adhesions 1 90.76 High High
Sepsis 92 88.32 High High
Vasoplegia 2 84.04 Quite High
Apoptosis 3 81.68 Quite High
INFLAMMATION 11 65.92 Quite High
Cv Unclassified Under Development 1 62.32 Quite High
Injury 3 60.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These include the release of IL-1, IL-2, IL-4, IL-6, IL-8, IL-10, tumor necrosis factor-alfa (TNF-alfa), platelet-activating factor, endorphins, nitric oxide, reactive oxygen species, tissue factor, macrophage migration inhibitory factor, and chemokines, which lead to a variety of immune system responses including vasodilatation, enhanced expression of adhesion molecules, increased capillary permeability, increased clot formation, and decreased fibrinolysis.
IL-4 Positive_regulation (activating) of IL-2 in capillary associated with chemokine, necrosis, cancer, increased venous pressure under development and adhesions
1) Confidence 0.02 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012437 Disease Relevance 0.99 Pain Relevance 0.16

General Comments

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