INT3531

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Context Info
Confidence 0.44
First Reported 1976
Last Reported 2005
Negated 0
Speculated 3
Reported most in Abstract
Documents 7
Total Number 9
Disease Relevance 1.48
Pain Relevance 2.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Adrb2) signal transduction (Adrb2) plasma membrane (Adrb2)
nucleus (Adrb2) cytoplasm (Adrb2) signal transducer activity (Adrb2)
Anatomy Link Frequency
myotubes 2
corpus 1
uterine 1
trachea 1
Adrb2 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 11 99.96 Very High Very High Very High
antagonist 12 99.44 Very High Very High Very High
Clonidine 7 99.32 Very High Very High Very High
sodium channel 6 98.48 Very High Very High Very High
abdominal pain 2 95.16 Very High Very High Very High
Dismenorea 4 91.24 High High
tetrodotoxin 3 81.84 Quite High
Pain 3 62.96 Quite High
adenocard 2 48.32 Quite Low
anesthesia 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Paralysis 8 99.48 Very High Very High Very High
Aggression 3 98.60 Very High Very High Very High
Convulsion 10 98.28 Very High Very High Very High
Abdominal Pain 2 95.16 Very High Very High Very High
Dysmenorrhea 3 91.24 High High
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of beta-adrenoceptor agonists on the clonidine-induced aggression in mice were studied.
Regulation (effects) of beta-adrenoceptor associated with aggression, agonist and clonidine
1) Confidence 0.44 Published 1986 Journal Pol J Pharmacol Pharm Section Abstract Doc Link 2883639 Disease Relevance 0.25 Pain Relevance 0.43
The present study used real-time confocal microscopy to examine the effects of the beta2-adrenoceptor agonist salbutamol on regulation of intracellular Ca2+ concentration ([Ca2+]i) in myotubes derived from neonatal mouse limb muscles.
Spec (examine) Regulation (effects) of beta2-adrenoceptor in myotubes associated with agonist
2) Confidence 0.29 Published 1999 Journal Am. J. Physiol. Section Abstract Doc Link 10329950 Disease Relevance 0 Pain Relevance 0.11
Effect of beta-adrenoceptor activation on [Ca2+]i regulation in murine skeletal myotubes.
Regulation (Effect) of beta-adrenoceptor in myotubes
3) Confidence 0.29 Published 1999 Journal Am. J. Physiol. Section Title Doc Link 10329950 Disease Relevance 0 Pain Relevance 0.12
The effects of the selective beta2-receptor stimulator terbutaline (0-25 to 0-5 mg given intravenously) on myometrial activity, local uterine blood flow, and lower abdominal pain were examined during the first day of menstruation in 11 women with severe primary dysmenorrhoea.
Spec (examined) Regulation (effects) of beta2-receptor in uterine associated with abdominal pain and dismenorea
4) Confidence 0.28 Published 1976 Journal Br J Obstet Gynaecol Section Abstract Doc Link 788773 Disease Relevance 0.41 Pain Relevance 0.53
We have tested the effects of phenylephrine, dobutamine and salbutamol, alpha-, beta 1- and beta 2-adrenoceptor agonists respectively, on the output of radiolabelled mucins into the cat trachea in situ.
Regulation (effects) of beta 2-adrenoceptor in trachea associated with agonist
5) Confidence 0.18 Published 1982 Journal Eur. J. Pharmacol. Section Abstract Doc Link 6126379 Disease Relevance 0 Pain Relevance 0.12
The effects of alpha 2-adrenoceptor agonists and antagonists were examined on seizure thresholds determined by intravenous infusions of convulsants in rodents. alpha 2-Adrenoceptor antagonists were proconvulsant; dose dependently reducing the threshold for pentylenetetrazol- or bicuculline-induced tonic seizures.
Regulation (effects) of 2-adrenoceptor associated with convulsion, antagonist and agonist
6) Confidence 0.07 Published 1988 Journal Eur. J. Pharmacol. Section Abstract Doc Link 2901362 Disease Relevance 0.38 Pain Relevance 0.38
In anesthetized, paralyzed patients, we studied the effects of beta2-adrenoceptor and DA1-receptor agonist dopexamine on ventilation perfusion distribution.
Regulation (effects) of beta2-adrenoceptor associated with agonist and paralysis
7) Confidence 0.01 Published 1998 Journal Anesth. Analg. Section Abstract Doc Link 9459241 Disease Relevance 0.27 Pain Relevance 0.05
We studied the effects of the beta2-adrenoceptor and DA1-receptor agonist dopexamine on ventilation perfusion (V(A)/Q) distribution in anesthetized, paralyzed patients (n = 17) undergoing major abdominal surgery.
Regulation (effects) of beta2-adrenoceptor associated with agonist and paralysis
8) Confidence 0.01 Published 1998 Journal Anesth. Analg. Section Abstract Doc Link 9459241 Disease Relevance 0.17 Pain Relevance 0.05
This study aimed to investigate the effects of non-selective (propranolol), and selective beta1- (atenolol, metoprolol and betaxolol) and beta2-adrenoceptor (ICI 118,551) antagonists in the nitric oxide (NO)-mediated rabbit corpus cavernosum relaxations induced by either electrical field stimulation (EFS) or activators of voltage-gated sodium channels.
Spec (investigate) Regulation (effects) of beta2-adrenoceptor in corpus associated with antagonist and sodium channel
9) Confidence 0.00 Published 2005 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16084509 Disease Relevance 0 Pain Relevance 0.46

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