INT353325

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.31
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (F2r) signal transducer activity (F2r)
Anatomy Link Frequency
bladder 2
F2r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 44 100.00 Very High Very High Very High
agonist 10 92.84 High High
Inflammatory stimuli 10 91.12 High High
interstitial cystitis 6 78.04 Quite High
cytokine 8 70.88 Quite High
substance P 4 51.68 Quite High
lidocaine 18 49.04 Quite Low
halothane 6 19.84 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
Thoracotomy 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 52 100.00 Very High Very High Very High
Cystitis 8 90.00 High High
Interstitial Cystitis 6 78.04 Quite High
Apoptosis 2 66.96 Quite High
Neurogenic Inflammation 2 46.80 Quite Low
Peripheral Arterial Disease 2 17.12 Low Low
Cancer 8 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cells were incubated for 1 hour at 37C and then exposed to thrombin at different concentrations (in sterile water; Sigma-Aldrich; St.
Positive_regulation (incubated) of Localization (exposed) of thrombin
1) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013117 Disease Relevance 0.07 Pain Relevance 0.03
Our current results suggest that one component of PAR1-mediated bladder inflammation may be release of MIF from urothelial cells and MIF upregulation.
Positive_regulation (upregulation) of Localization (release) of PAR1 in bladder associated with inflammation
2) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013117 Disease Relevance 1.24 Pain Relevance 0.73

General Comments

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