INT353326

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 1.28
Pain Relevance 1.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Mif) cell proliferation (Mif) extracellular space (Mif)
aging (Mif) extracellular region (Mif) nucleus (Mif)
Anatomy Link Frequency
bladder 2
Mif (Rattus norvegicus)
Pain Link Frequency Relevance Heat
lidocaine 36 99.98 Very High Very High Very High
substance P 8 99.98 Very High Very High Very High
Inflammation 88 98.86 Very High Very High Very High
cytokine 16 90.28 High High
Inflammatory stimuli 20 80.64 Quite High
agonist 20 64.24 Quite High
interstitial cystitis 12 49.44 Quite Low
halothane 12 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Thoracotomy 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurogenic Inflammation 4 98.86 Very High Very High Very High
INFLAMMATION 104 97.80 Very High Very High Very High
Cystitis 16 87.52 High High
Interstitial Cystitis 12 49.44 Quite Low
Apoptosis 4 38.36 Quite Low
Cancer 16 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Overdose 4 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In fact, our earlier results investigating MIF release during neurogenic inflammation (Substance P-evoked) showed that intravesical lidocaine abolished MIF release in that model [27], and thus are different from findings in the present study.
Negative_regulation (abolished) of Localization (release) of MIF associated with inflammation, neurogenic inflammation, lidocaine and substance p
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013117 Disease Relevance 0.46 Pain Relevance 0.50
In rats, thrombin-induced MIF release was reduced but not abolished by intravesical lidocaine treatment.
Neg (not) Negative_regulation (abolished) of Localization (release) of MIF associated with lidocaine
2) Confidence 0.33 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC3013117 Disease Relevance 0 Pain Relevance 0.26
In rats, thrombin-induced MIF release was reduced but not abolished by intravesical lidocaine treatment.
Neg (not) Negative_regulation (reduced) of Localization (release) of MIF associated with lidocaine
3) Confidence 0.33 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC3013117 Disease Relevance 0 Pain Relevance 0.26
We showed previously that substance P elicits MIF release from the bladder in general, and urothelium in particular, dependent on bladder nerve activation [9], [10], [24].
Negative_regulation (elicits) of Localization (release) of MIF in bladder associated with substance p
4) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013117 Disease Relevance 0.82 Pain Relevance 0.57

General Comments

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