INT353361

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Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cxcr4, Cxcl12) endosome (Cxcr4) extracellular space (Cxcl12)
signal transduction (Cxcr4) extracellular region (Cxcl12) cytoplasmic membrane-bounded vesicle (Cxcr4)
Anatomy Link Frequency
neurons 2
Cxcr4 (Mus musculus)
Cxcl12 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 9 95.76 Very High Very High Very High
Hippocampus 35 66.20 Quite High
Central nervous system 7 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Convulsion 44 5.00 Very Low Very Low Very Low
Status Epilepticus 19 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 12 5.00 Very Low Very Low Very Low
Epilepsy 8 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In culture, ESNPs, as well as ESC-derived immature neurons, expressed CXCR4, a receptor for CXCL12 required for CXCL12-mediated chemotaxis (Figure 3A, B).
Positive_regulation (required) of CXCR4 Binding (receptor) of CXCL12 in neurons
1) Confidence 0.46 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013129 Disease Relevance 0 Pain Relevance 0.17

General Comments

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