INT353394

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 4.80
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein folding (NFYC) nucleus (NFYC) intracellular (NFYC)
DNA binding (NFYC)
Anatomy Link Frequency
brain 2
NFYC (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 276 99.68 Very High Very High Very High
Nicotine 56 99.46 Very High Very High Very High
amygdala 68 86.84 High High
insula 16 75.96 Quite High
Anterior cingulate cortex 36 75.64 Quite High
Thalamus 8 44.00 Quite Low
imagery 24 42.40 Quite Low
depression 16 29.28 Quite Low
alcohol 32 5.00 Very Low Very Low Very Low
cocaine 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 620 100.00 Very High Very High Very High
Drug Dependence 32 97.20 Very High Very High Very High
Cognitive Disorder 24 55.60 Quite High
Depression 20 29.28 Quite Low
Anxiety Disorder 8 28.56 Quite Low
Attention Deficit Hyperactivity Disorder 16 12.16 Low Low
Impulse Control Disorders 72 5.00 Very Low Very Low Very Low
Recurrence 20 5.00 Very Low Very Low Very Low
Mental Disorders 8 5.00 Very Low Very Low Very Low
Handedness 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mean FTND score in the HSM group was low (M = 4.0; SD = 1.5) compared with FTND scores in smokers reported in other fMRI cue reactivity studies (Franklin et al. 2007, FTND = 4.8; McClernon et al. 2007, FTND = 6.4; McClernon, Kozink & Rose 2008, FTND = 6.5), and no nicotine dependence diagnoses were available for the HSM, as in other studies (Brody et al. 2002).
Neg (no) Gene_expression (available) of HSM associated with addiction, nicotine addiction and nicotine
1) Confidence 0.37 Published 2010 Journal Addiction Biology Section Body Doc Link PMC3014110 Disease Relevance 1.64 Pain Relevance 0.52
Craving for gambling was higher in PRG compared with HSM and HC, F(2,51) = 6.92, P < 0.002, and a trend for increased gambling craving after the cue reactivity task was observed in PRG, F(1,16) = 3.18, P = 0.09, partial ?
Gene_expression (higher) of HSM associated with nicotine addiction
2) Confidence 0.37 Published 2010 Journal Addiction Biology Section Body Doc Link PMC3014110 Disease Relevance 0.93 Pain Relevance 0.21
Increased brain activation in related fronto-limbic brain areas was present in HSM with higher FTND scores compared with HSM with lower FTND scores.



Gene_expression (present) of HSM in brain associated with nicotine addiction
3) Confidence 0.37 Published 2010 Journal Addiction Biology Section Abstract Doc Link PMC3014110 Disease Relevance 1.12 Pain Relevance 0.34
Increased brain activation in related fronto-limbic brain areas was present in HSM with higher FTND scores compared with HSM with lower FTND scores.



Gene_expression (present) of HSM in brain associated with nicotine addiction
4) Confidence 0.37 Published 2010 Journal Addiction Biology Section Abstract Doc Link PMC3014110 Disease Relevance 1.11 Pain Relevance 0.34

General Comments

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