INT353440

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Rnd3, Rnd3, Rock1) intracellular (Rnd3, Rnd3) cytoskeleton (Rock1)
cytoskeleton organization (Rock1) kinase activity (Rock1) cytoplasm (Rock1)
Rnd3 (Mus musculus)
Rnd3 (Mus musculus)
Rock1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 37 50.00 Quite Low
Severe Combined Immunodeficiency 4 23.04 Low Low
Metastasis 16 5.00 Very Low Very Low Very Low
Sarcoma 14 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 5 5.00 Very Low Very Low Very Low
Carcinoma 4 5.00 Very Low Very Low Very Low
Skin Cancer 3 5.00 Very Low Very Low Very Low
Synovial Sarcoma 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the Rnd3 expressing clones we did find lower level of p-MLC than in parental and mock-transfected cells, which could be due to an Rnd3-induced reduction in ROCK kinase activity (Fig. 5F).
Rnd3 Positive_regulation (induced) of Rnd3 Negative_regulation (reduction) of ROCK kinase
1) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3014295 Disease Relevance 0 Pain Relevance 0

General Comments

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