INT353448

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (BRCA1, CCL2) nucleoplasm (BRCA1) aging (CCL2)
chromosome segregation (BRCA1) DNA binding (BRCA1) extracellular space (CCL2)
BRCA1 (Homo sapiens)
CCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 36 100.00 Very High Very High Very High
Inflammation 37 77.92 Quite High
fibrosis 1 69.44 Quite High
Central nervous system 18 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immune Reconstitution Inflammatory Syndrome 222 100.00 Very High Very High Very High
Cryptococcal Meningitis 102 99.98 Very High Very High Very High
INFLAMMATION 39 77.92 Quite High
Infection 11 71.12 Quite High
Fibrosis 1 69.44 Quite High
Mycobacterial Infection 6 63.16 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 48 50.00 Quite Low
Fungal Infection 2 21.08 Low Low
Death 17 5.00 Very Low Very Low Very Low
Cryptococcus Infection 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesize that the abnormal cytokine profiles we observed before CM-IRIS, including elevations of Th2 cytokine (e.g., IL-4, IL-13) and lack of proinflammatory cytokines such as TNF-?
IRIS Positive_regulation (elevations) of Th2 cytokine associated with cryptococcal meningitis, immune reconstitution inflammatory syndrome and cytokine
1) Confidence 0.01 Published 2010 Journal PLoS Medicine Section Body Doc Link PMC3014618 Disease Relevance 1.37 Pain Relevance 0.26

General Comments

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