INT353565

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Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SELENBP1) nucleolus (SELENBP1) nucleus (SELENBP1)
cytoplasm (SELENBP1)
Anatomy Link Frequency
uterine 1
band 1
SELENBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
pain pelvic 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Uterine Fibroids 304 99.56 Very High Very High Very High
Cancer 108 99.02 Very High Very High Very High
Generaliased Trisomy 4 73.04 Quite High
Ovarian Cancer 4 72.32 Quite High
Endometriosis (extended) 4 69.68 Quite High
Adenocarcinoma 4 45.48 Quite Low
Obesity 4 26.12 Quite Low
Carcinoma 8 5.00 Very Low Very Low Very Low
Reprotox - General 3 8 5.00 Very Low Very Low Very Low
Infarction 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Western Blot analysis using anti-human SELENBP1 recognized a single band at 56 kDa in all samples examined.
SELENBP1 Spec (examined) Binding (recognized) of in band
1) Confidence 0.48 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC3014888 Disease Relevance 0.79 Pain Relevance 0
The anti-cancer action of selenium is thought to be mediated by selenium-binding protein 1 (SELENBP1), a 56 kDa intracellular protein, that binds covalently to selenium.
selenium-binding protein 1 Binding (binds) of associated with cancer
2) Confidence 0.48 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC3014888 Disease Relevance 1.27 Pain Relevance 0
The anti-cancer action of selenium is thought to be mediated by selenium-binding protein 1 (SELENBP1), a 56 kDa intracellular protein, that binds covalently to selenium.
SELENBP1 Binding (binds) of associated with cancer
3) Confidence 0.48 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC3014888 Disease Relevance 1.25 Pain Relevance 0
Our study showing a decreased expression of SELENBP1 in uterine leiomyoma not only indicates a role of SELENBP1 in tumorigenesis but also suggests the potential utility of selenium in prevention and treatment of uterine leiomyoma.
SELENBP1 Binding (role) of in uterine associated with uterine fibroids
4) Confidence 0.37 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC3014888 Disease Relevance 1.18 Pain Relevance 0

General Comments

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