INT35363

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Context Info
Confidence 0.36
First Reported 1988
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.94
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GH1, GHRH) extracellular region (GH1, GHRH) cell-cell signaling (GHRH)
GH1 (Homo sapiens)
GHRH (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 1 84.08 Quite High
Clonidine 3 83.44 Quite High
depression 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Syndrome 3 94.48 High High
Depression 4 88.48 High High
Dwarfism 3 75.00 Quite High
Microcephaly 1 63.28 Quite High
Pressure Volume 2 Under Development 1 62.16 Quite High
Hypoglycemia 2 57.72 Quite High
Cleidocranial Dysplasia 1 56.96 Quite High
Congenital Anomalies 1 55.76 Quite High
Obesity 1 54.48 Quite High
Growth Problems 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared to controls, depressed patients showed a significant attenuation of net growth hormone (GH) responses to GHRH associated with normal basal GH concentrations.
GH Binding (associated) of GHRH
1) Confidence 0.36 Published 1988 Journal Psychiatry Res Section Abstract Doc Link 3141943 Disease Relevance 0.23 Pain Relevance 0.30
Relatives heterozygous for the mutation had moderately decreased IGF-I levels and slightly blunted GH responses to GHRH and L-dopa, but they showed only minimal or no height deficit.
GH Binding (blunted) of GHRH
2) Confidence 0.16 Published 1998 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 9814493 Disease Relevance 0.72 Pain Relevance 0.06

General Comments

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