INT35367

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Context Info
Confidence 0.61
First Reported 1988
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.45
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (Galns) lysosome (Galns)
Anatomy Link Frequency
canals 1
Galns (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 10 97.24 Very High Very High Very High
Pain 2 95.64 Very High Very High Very High
Sciatica 1 90.48 High High
substance P 1 87.36 High High
Somatostatin 1 83.88 Quite High
opiate 3 75.00 Quite High
antagonist 1 64.96 Quite High
opioid receptor 1 57.44 Quite High
Disease Link Frequency Relevance Heat
Periapical Periodontitis 2 98.88 Very High Very High Very High
Pain 2 95.64 Very High Very High Very High
Nerve Root Compression 1 90.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Nucleolytic action of chondroitinase ABC on the lumbar disc of the rabbit].
Gene_expression (action) of chondroitinase ABC
1) Confidence 0.61 Published 1988 Journal C. R. Acad. Sci. III, Sci. Vie Section Title Doc Link 3142653 Disease Relevance 0.09 Pain Relevance 0.09
The object of this study was to determine the correlation between clinical symptoms and the activity of enzymes such as collagenase, chondroitinase, and hyaluronidase produced by bacteria isolated from infected root canals.
Gene_expression (produced) of chondroitinase in canals
2) Confidence 0.19 Published 1994 Journal J Endod Section Abstract Doc Link 8006569 Disease Relevance 0.17 Pain Relevance 0.08
Bacteria producing collagenase or chondroitinase and hyaluronidase were found to be significantly related to subacute clinical symptoms involving percussion pain.
Gene_expression (producing) of chondroitinase associated with pain
3) Confidence 0.19 Published 1994 Journal J Endod Section Abstract Doc Link 8006569 Disease Relevance 0.19 Pain Relevance 0.10
Chemotactic properties were abolished by pretreating cells with heparinase, chondroitinase, sodium chlorate, and anti-syndecan-4 antibodies, indicating the involvement of syndecan-4.
Gene_expression (pretreating) of chondroitinase
4) Confidence 0.03 Published 2004 Journal Biochemistry Section Abstract Doc Link 14705951 Disease Relevance 0 Pain Relevance 0.63

General Comments

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