INT353690

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.17
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ca2) extracellular space (Ca2) lyase activity (Ca2)
plasma membrane (Grin2b) embryo development (Grin2b) response to stress (Ca2)
Anatomy Link Frequency
neuronal 1
Grin2b (Rattus norvegicus)
Ca2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 66 100.00 Very High Very High Very High
Glutamate 36 100.00 Very High Very High Very High
ischemia 110 98.86 Very High Very High Very High
bDMF 6 91.00 High High
Glutamate receptor 6 5.00 Very Low Very Low Very Low
isoflurane 6 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 18 99.16 Very High Very High Very High
Brain Hemorrhage 76 98.86 Very High Very High Very High
Death 10 93.96 High High
Parkinson's Disease 2 93.36 High High
Cv Unclassified Under Development 30 74.48 Quite High
Apoptosis 2 68.88 Quite High
Infarction 6 5.00 Very Low Very Low Very Low
Hypoxia 6 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 4 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The most remarkable decrease of neural (NeuN) and astroglial protein (GFAP) 24 h after focal cerebral ischemia supports evidence demonstrating that increased NCX1 and NR2B-containing NMDA receptor is closely associated with Ca2+-dependent neuronal injury in the penumbra.
NR2B-containing Binding (associated) of Ca2 in neuronal associated with brain hemorrhage, nmda receptor, ischemia and injury
1) Confidence 0.14 Published 2010 Journal Anatomy & Cell Biology Section Body Doc Link PMC3015038 Disease Relevance 0.58 Pain Relevance 0.33
Significant increase of NR2A 3 h after focal cerebral ischemia might couple with the compensatory response to diminish the Ca2+ which is associated with lower affinity for glutamate and considerably shorter offset decay time for Ca2+ compared with those of NR2B-containing NMDA receptors.
NR2B-containing Binding (associated) of Ca2 associated with brain hemorrhage, glutamate, nmda receptor and ischemia
2) Confidence 0.14 Published 2010 Journal Anatomy & Cell Biology Section Body Doc Link PMC3015038 Disease Relevance 0.59 Pain Relevance 0.67

General Comments

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