INT353787

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Pcsk9) extracellular space (Pcsk9) extracellular region (Pcsk9)
lipid metabolic process (Pcsk9) lysosome (Pcsk9)
Pcsk9 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 7 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperlipidemia 19 97.24 Very High Very High Very High
Hyperlipoproteinemia Type Ii 66 96.46 Very High Very High Very High
Disorder Of Lipid Metabolism 18 91.44 High High
Erythema 1 76.40 Quite High
Cold Sores 1 47.44 Quite Low
Epstein-barr Virus 4 19.16 Low Low
Atherosclerosis 16 5.00 Very Low Very Low Very Low
Targeted Disruption 15 5.00 Very Low Very Low Very Low
Coronary Artery Disease 12 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While the majority of studies were focused on treating FH by inhibition of hypercholesterolaemia through up-regulation of LDLR or other surrogate lipoprotein receptors (as will be discussed later), an alternative approach was to down-regulate apoB-100 LDLR-ligand or PCSK9 [63] expression.
Regulation (regulate) of Gene_expression (expression) of PCSK9 associated with hyperlipoproteinemia type ii and hyperlipidemia
1) Confidence 0.24 Published 2010 Journal Int Arch Med Section Body Doc Link PMC3016243 Disease Relevance 0.36 Pain Relevance 0

General Comments

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