INT353939

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Rorc) nucleus (Rorc) DNA binding (Rorc)
Anatomy Link Frequency
Th17 cells 1
Rorc (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 31 98.44 Very High Very High Very High
chemokine 2 88.00 High High
Crohn's disease 48 67.72 Quite High
Inflammation 21 61.04 Quite High
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 54 74.76 Quite High
Disease 53 67.72 Quite High
INFLAMMATION 20 61.04 Quite High
Sprains And Strains 1 48.52 Quite Low
Ileal Diseases 5 23.44 Low Low
Ileitis 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Colon Disease 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Polyps 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The differentiation of Th17 cells depends on the activation of janus kinase 2 (JAK2), signal transducer and activator of transcription 3 (STAT3) and the transcription factor RAR-related organ receptor C2 (RORC2) and is regulated by a combination of cytokines, including IL-6, IL-1B (IL-1?)
Positive_regulation (activation) of RORC2 in Th17 cells associated with cytokine
1) Confidence 0.33 Published 2010 Journal BMC Immunol Section Body Doc Link PMC3016394 Disease Relevance 0.45 Pain Relevance 0.35

General Comments

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