INT353968

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Context Info
Confidence 0.44
First Reported 2011
Last Reported 2011
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 2
Pet1 2
Pet1 (Mus musculus)
Pain Link Frequency Relevance Heat
Raphe 32 98.20 Very High Very High Very High
Neurotransmitter 4 93.00 High High
depression 2 57.04 Quite High
Serotonin 6 50.00 Quite Low
Dopamine 16 13.32 Low Low
Somatosensory cortex 2 10.80 Low Low
medulla 6 5.00 Very Low Very Low Very Low
Locus ceruleus 4 5.00 Very Low Very Low Very Low
monoamine 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mental Disorders 6 59.12 Quite High
Depression 2 57.04 Quite High
Post-traumatic Stress Disorder 2 55.84 Quite High
Anxiety Disorder 2 29.76 Quite Low
Body Weight 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, normal Pet1 expression was found in Lmx1b iCKO mice.
Regulation (found) of Gene_expression (expression) of Pet1 in Pet1
1) Confidence 0.44 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3016403 Disease Relevance 0.17 Pain Relevance 0.15
In contrast, the expression of both Pet1 and Aadc appeared unchanged in Lmx1b iCKO mice relative to control mice, indicating that there was no loss of 5-HTergic neurons in the raphe nuclei.
Neg (unchanged) Spec (appeared) Regulation (unchanged) of Gene_expression (expression) of Pet1 in neurons associated with raphe
2) Confidence 0.44 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3016403 Disease Relevance 0 Pain Relevance 0.13

General Comments

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