INT353977

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Context Info
Confidence 0.26
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Tph2)
Anatomy Link Frequency
neurons 2
Tph2 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 8 88.88 High High
monoamine 2 85.04 High High
Serotonin 3 83.32 Quite High
Raphe 16 75.00 Quite High
medulla 3 5.00 Very Low Very Low Very Low
Locus ceruleus 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 3 5.00 Very Low Very Low Very Low
Mental Disorders 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Post-traumatic Stress Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results reveal that Lmx1b is required for the biosynthesis of 5-HT in adult mouse brain, and it may be involved in maintaining normal functions of central 5-HTergic neurons by regulating the expression of Tph2, Sert and Vmat2.



Regulation (regulating) of Gene_expression (expression) of Tph2 in neurons
1) Confidence 0.26 Published 2011 Journal PLoS ONE Section Abstract Doc Link PMC3016403 Disease Relevance 0 Pain Relevance 0.24

General Comments

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