INT353981

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Context Info
Confidence 0.53
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Lmx1b) cell death (Lmx1b) nucleus (Lmx1b)
DNA binding (Lmx1b)
Anatomy Link Frequency
neurons 2
Pet1 (Mus musculus)
Lmx1b (Mus musculus)
Pain Link Frequency Relevance Heat
Raphe 16 97.52 Very High Very High Very High
Dopamine 8 71.76 Quite High
monoamine 2 59.68 Quite High
Serotonin 3 50.00 Quite Low
Substantia nigra 1 37.20 Quite Low
Ventral tegmentum 1 35.52 Quite Low
Locus ceruleus 2 30.88 Quite Low
medulla 3 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 3 5.00 Very Low Very Low Very Low
Mental Disorders 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Post-traumatic Stress Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, Pet1 expression in 5-HTergic neurons requires Lmx1b during embryonic development [12], but its expression in the raphe nuclei of Lmx1b iCKO mice showed no difference from wild-type controls (Figure 5Q–T).
Gene_expression (expression) of Pet1 in neurons Positive_regulation (requires) of Lmx1b associated with raphe
1) Confidence 0.53 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3016403 Disease Relevance 0 Pain Relevance 0.23

General Comments

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