INT35399

Context Info Confidence 0.01 First Reported 1988 Last Reported 1988 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 1.14

cytoplasm (Alox5, Mthfs) mitochondrion (Mthfs) nuclear envelope (Alox5) Golgi apparatus (Mthfs) ligase activity (Mthfs) cytosol (Alox5)

Alox5 (Mus musculus) Mthfs (Mus musculus)

Pain Link Frequency Relevance Heat Analgesic 12 99.68 cINOD 2 93.76 Bioavailability 2 74.28 Pain 4 25.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

BW775C was also analgesic, but inhibited cyclo-oxygenase, 5-lipoxygenase and 12-HETE formation.

lipoxygenase Binding (formation) of cyclo-oxygenase associated with analgesic

1) Confidence 0.01 Published 1988 Journal J Pharmacol Methods Section Abstract Doc Link 3145369 Disease Relevance 0 Pain Relevance 0.57

BW775C was also analgesic, but inhibited cyclo-oxygenase, 5-lipoxygenase and 12-HETE formation.

lipoxygenase Binding (formation) of cyclo-oxygenase associated with analgesic

2) Confidence 0.01 Published 1988 Journal J Pharmacol Methods Section Abstract Doc Link 3145369 Disease Relevance 0 Pain Relevance 0.57

General Comments

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