INT354038

Context Info Confidence 0.41 First Reported 2011 Last Reported 2011 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.60 Pain Relevance 0.07

signal transduction (Avpr1b) plasma membrane (Avpr1b) response to stress (Avpr1b) signal transducer activity (Avpr1b)

Anatomy Link Frequency pancreas 2 Avpr1b (Mus musculus)

Pain Link Frequency Relevance Heat medulla 6 88.56 antagonist 17 49.08 agonist 9 48.44 Catecholamine 3 45.12 depression 8 5.00 Hippocampus 4 5.00 Potency 2 5.00 ketamine 1 5.00 Morphine 1 5.00 amygdala 1 5.00

Disease Link Frequency Relevance Heat Obesity 3 99.04 Targeted Disruption 60 98.72 Diabetes Mellitus 1 73.24 Stress 80 5.00 Aggression 17 5.00 Sprains And Strains 12 5.00 Depression 10 5.00 Anxiety Disorder 8 5.00 Hypersensitivity 3 5.00 Hypoglycemia 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Whether this is due to a lack of Avpr1b influence in the pancreas, white adipose tissue, or both, is unclear.

Negative_regulation (lack) of Regulation (influence) of Avpr1b in pancreas associated with obesity

1) Confidence 0.41 Published 2011 Journal Stress (Amsterdam, Netherlands) Section Body Doc Link PMC3016603 Disease Relevance 0.60 Pain Relevance 0.07

General Comments

This test has worked.