INT354071

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Context Info
Confidence 0.12
First Reported 2011
Last Reported 2011
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Pomc, Cort) signal transduction (Pomc) generation of precursor metabolites and energy (Pomc)
extracellular space (Pomc) cell-cell signaling (Pomc) cytoplasm (Pomc)
Pomc (Mus musculus)
Cort (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 6 61.84 Quite High
Serotonin 1 24.20 Low Low
antagonist 17 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
Catecholamine 3 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 60 98.42 Very High Very High Very High
Stress 80 97.74 Very High Very High Very High
Hypersensitivity 3 44.32 Quite Low
Aggression 17 5.00 Very Low Very Low Very Low
Sprains And Strains 12 5.00 Very Low Very Low Very Low
Depression 10 5.00 Very Low Very Low Very Low
Anxiety Disorder 8 5.00 Very Low Very Low Very Low
Obesity 3 5.00 Very Low Very Low Very Low
Hypoglycemia 3 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Where stress-induced ACTH release in Avpr1b KO mice is not always followed by a proportional CORT attenuation, suggests that CORT may be released independently of ACTH in some circumstances.
ACTH Neg (independently) Positive_regulation (independently) of Localization (released) of CORT associated with targeted disruption and stress
1) Confidence 0.12 Published 2011 Journal Stress (Amsterdam, Netherlands) Section Body Doc Link PMC3016603 Disease Relevance 0.86 Pain Relevance 0.03

General Comments

This test has worked.

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