INT354095

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NFKB2) extracellular matrix organization (NFKB2) DNA binding (NFKB2)
cytoplasm (NFKB2) cytosol (NFKB2) signal transduction (NFKB2)
Anatomy Link Frequency
myotubes 1
NFKB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 11 11.20 Low Low
depression 3 7.92 Low Low
antidepressant 1 6.08 Low Low
antagonist 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Cannabinoid 3 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Appetite Loss 90 100.00 Very High Very High Very High
Apoptosis 1 99.44 Very High Very High Very High
Cancer 36 66.04 Quite High
Pancreatic Cancer 3 65.52 Quite High
Congenital Anomalies 11 54.44 Quite High
Disease 2 28.24 Quite Low
Constipation 1 23.04 Low Low
Xerostomia 1 22.32 Low Low
Weight Gain 2 21.88 Low Low
Obesity 3 20.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Initial studies using animal models have demonstrated that NFkB is upregulated in CC increasing proteolysis and inducing apoptosis in myotubes [43, 44].
Protein_catabolism (proteolysis) of NFkB in myotubes associated with appetite loss and apoptosis
1) Confidence 0.12 Published 2010 Journal Curr Treat Options Oncol Section Body Doc Link PMC3016925 Disease Relevance 0.99 Pain Relevance 0

General Comments

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